产品名称

(R)-Butaprost

一般描述

(R)-Butaprost is a selective EP2 prostanoid receptor agonist.

别称

(1R,2R,3R)-3-Hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)-1-butenyl]-5-oxo-cyclopentaneheptanoic acid methyl ester

纯 度

≥98.0%(HPLC)

CAS NO.

69648-38-0

分子式

C²⁴H⁴⁰O⁵

分子量

408.57

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

淡黄色油状物

溶解性(25℃)

DMSO

freely soluble

乙醇

freely soluble

l  生物学信息

生物活性/药理作用

Butaprost comprises hydroxy-cyclopentanone ring and ω-chain.It aids protection in events of glutamate based N-methyl-D-aspartate receptor toxicity.Butaprost inhibits conjunctival fibrosis and lowers the intraocular pressure in post glaucoma filtration surgery.It also promotes wound healing by reducing the subconjunctival scarring Tenon′s fibroblasts. Butaprost plays a protective role in pulmonary fibrosis and aids protection against the aggregated amyloid β (Aβ) peptides in Alzheimer′s disease.

(R)-Butaprost is a selective EP2 prostanoid receptor agonist.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov