产品名称

Psychosine from bovine brain

一般描述

Psychosine is a neurotoxic lysosphingolipid and a glycolipid precursor for the synthesis of cerebrosides.

别称

1-β-D-Galactosylsphingosine

纯 度

≥98.0%(TLC)

CAS NO.

2238-90-6

分子式

C²⁴H⁴⁷NO⁷

分子量

461.63

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

White to Off White powder

l  生物学信息

生物活性/药理作用

Psychosine is a neurotoxic lysosphingolipid and a glycolipid precursor for the synthesis of cerebrosides. It is synthesized from galactosylceramide, phrenosin. Elevated psychosine levels are implicated in Krabbe disease. It mediates demyelination and consequently oligodendrocytes degeneration. Psychosine is also correlated to neurological disease, Globoid cell leukodystrophy (GLD), where in galactosylceramidase (GALC) enzyme deficiency leads to its accumulation.

应用

Psychosine has been used as a lipid in lipid-protein overlay binding assay.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov