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Gramicidin from Bacillus aneurinolyticus (Bacillus brevis)

商品编号: S1205
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备注:

国外库存,货期2-4周,具体详情请联系销售人员。

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详细介绍

l  基本信息

产品名称

Gramicidin from Bacillus aneurinolyticus (Bacillus brevis)(葛米素来源于解硫胺素芽胞杆菌短芽孢杆菌))

一般描述

Linear polypeptide antibiotic complex.

别 称

Gramicidine; Gramicidinum

纯 度

Linear polypeptide antibiotic complex. A  mixture of gramicidins A, B, C, and D.

CAS NO.

1405-97-6

分子式

C99H140N20O17

分子量

1882.332

适用范围

生物试剂,适用于细胞培养等

l  理化信息

外 观

白色至灰白色粉末或结晶粉末

l  生物学信息

生物活性/药理作用

Linear polypeptide antibiotic mixture of gramicidin A, B, C, and D. Gramicidin A acts as neutral carrier and helps in the establishment of ion flux across the lipid b.Gramicidin D, a channel-forming ionophore that flip-flops slowly across the membrane is a known Pgp substrate and surprisingly was found to inhibit Pgp ATPase activity. This inhibition was reversed by other Pgp substrates suggesting a common drug binding site among MDR substrate-type drugs and chemosensitizers.

应 用

Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) has been used as a control to measure the rate of diffusion of protonated β-lactams through the lipid b in liposome swelling assay. It has also been used as an analyte for the purpose of infrared laser desorption or ionization from silicon.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov