产品名称

加巴喷丁盐酸盐(Gabapentin HCl)

一般描述

Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.

别 称

1-(Aminomethyl)-cyclohexaneacetic acid hydrochloride;Neurontin HCl; Gabapentine HCl;

纯 度

≥98% (HPLC)

CAS NO.

60142-95-2

分子式

C⁹H¹⁷NO²·HCl

分子量

207.7

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解度(25℃)

DMSO

Very slightly soluble

乙醇

Very slightly soluble

水

≥35mg/mL

l  生物学信息

生物活性/药理作用

Gabapentin, an analog of GABA, is used as an anticonvulsant to treat partial seizures, amyotrophic lateral sclerosis (ALS), and painful neuropathies. Potential uses include monotherapy of refractory partial seizure disorders, and treatment of spasticity in multiple   sclerosis, tremor. mood disorders, and attenuation of disruptive behaviors in dementia. Gabapentin has high lipid solubility, is not metabolized by the liver, has no protein binding, and doesn't possess the usual drug interactions.

Gabapentin is a synthetic analogue of the neurotransmitter gamma-aminobutyric acid with anticonvulsant activity. Although its exact mechanism of action is unknown, gabapentin appears to inhibit excitatory neuron activity. This agent also exhibits analgesic properties.

l  包装与存储

包 装

50mg; 250mg;1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.     http://www.drugbank.ca

2.     https://ncit.nci.nih.gov

3.     https://www.ncbi.nlm.nih.gov/mesh