产品名称

盐酸洛美沙星(Lomefloxacin HCl)

一般描述

Lomefloxacin HCl is the hydrochloride salt of Lomefloxacin. Lomefloxacin is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.

别 称

1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

纯 度

≥98% (HPLC)

CAS NO.

98079-52-8

分子式

C¹⁷H¹⁹F²N³O³·HCl

分子量

387.81

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解度(25℃)

DMSO

~1mg/mL

乙醇

Insoluble

水

~5mg/mL

l  生物学信息

生物活性/药理作用

Lomefloxacin is a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis.

l  包装与存储

包 装

50mg; 1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov