产品名称

硫酸博莱霉素(Bleomycin sulfate)

一般描述

Bleomycin Sulfate(硫酸博莱霉素) is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus.

含 量

1500-2000 IU/mg(Dried Basis)

CAS NO.

9041-93-4

分子式

C⁵⁵H⁸⁵N¹⁷O²⁵S⁴

分子量

1512.619

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或黄白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

~2mg/mL

水

≥50mg/mL

l  生物学信息

生物活性/药理作用

Bleomycin Sulfate is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin sulfate forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.

l  包装与存储

包 装

5mg; 25mg

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov