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详细介绍
l 基本信息 |
产品名称 | 芦荟大黄素(Aloe-emodin) |
一般描述 | Aloe-emodin(芦荟大黄素) is an interferon-inducing agent with a strong stimulant-laxative action. |
别 称 | 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone,
3-Hydroxymethylchrysazine; Aloe-emodine; Aloeemodin |
纯 度 | ≥98%(HPLC) | CAS NO. | 481-72-1 |
分子式 | C15H10O5 | 分子量 | 270.24 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 棕色固体 |
溶解性(25℃) | DMSO | ~3mg/mL |
乙醇 | Insoluble |
水 | Insoluble |
l 生物学信息 |
生物活性/药理作用 | Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin. |
l 包装与存储 |
包 装 | 1g |
存储温度 | 0-5℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |