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详细介绍
l 基本信息 |
产品名称 | 安塞曲匹(Anacetrapib) |
一般描述 | Anacetrapib(安塞曲匹) is a cholesteryl ester transfer protein (CETP) inhibitor with hypocholesterolemic properties. |
别 称 | (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-one; MK0859 |
纯 度 | ≥98%(HPLC) | CAS NO. | 875446-37-0 |
分子式 | C30H25F10NO3 | 分子量 | 637.518 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色或类白色固体 |
溶解性(25℃) | DMSO | ≥50mg/mL |
乙醇 | ≥50mg/mL |
水 | Insoluble |
l 生物学信息 |
生物活性/药理作用 | Anacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor with hypocholesterolemic properties. Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol levels. This agent has not yet been shown to reduce deaths associated with hypercholesterolemia. |
l 包装与存储 |
包 装 | 10mg; 50mg; 250mg |
存储温度 | 0-5℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
