产品名称

呋塞米(Furosemide)

一般描述

Furosemide(呋塞米), a sulfamoylanthranilic acid derivative, is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, widely used to treat hypertension and edema.

别 称

5-(Aminosulfonyl)-4-chloro-2-([2-furanylmethyl]amino)benzoic acid; Frusemide; Furosemid;  Furanthril

纯 度

≥98%(HPLC)

CAS NO.

54-31-9

分子式

C¹²H¹¹ClN²O⁵S 

分子量

330.74

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

Insoluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Furosemide, a sulfonamide-type loop diuretic structurally related to bumetanide, is used to manage hypertension and edema associated with congestive heart failure, cirrhosis, and renal disease, including the nephrotic syndrome.

Furosemide is a sulfamoylanthranilic acid derivative, also known as frusemide, and potent loop diuretic. Furosemide is widely used to treat hypertension and edema. This agent is highly bound to albumin and is largely excreted unchanged in the urine.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov