产品名称

磺胺吡啶(Sulfapyridine)

一般描述

Sulfapyridine(磺胺吡啶)  is only found in individuals that have used or taken this drug. It is an antibacterial, potentially toxic, used to treat certain skin diseases.

别 称

4-Amino-N-[2-pyridyl]benzene sulfonamide

纯 度

≥98%(HPLC)

CAS NO.

144-83-2

分子式

C¹¹H¹¹N³O²S

分子量

249.29

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

~2mg/mL

乙醇

Insoluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Sulfapyridine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble  sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfapyridine is a short-acting sulfonamide  antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov