产品名称

甲硝唑(Metronidazole)

一般描述

Metronidazole(甲硝唑) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.

别 称

2-(2-methyl-5-nitroimidazol-1-yl)ethanol; Metronidazol; Anagiardil

纯 度

≥98%(HPLC)

CAS NO.

443-48-1

分子式

C⁶H⁹N³O³

分子量

171.156

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥30mg/mL

乙醇

Insoluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov