产品名称

泮托拉唑钠(Pantoprazole SodiuM Salt)

一般描述

Pantoprazole Sodium(泮托拉唑钠)  is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity.

别 称

sodium;5-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]benzimidazol-1-ide; Pantoloc; Controloc; Pantecta; Zurcal

纯 度

≥98%(HPLC)

CAS NO.

138786-67-1

分子式

C¹⁶H¹⁴F²N³NaO⁴S

分子量

405.35

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

淡粉色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

≥50mg/mL

水

≥50mg/mL

l  生物学信息

生物活性/药理作用

Pantoprazole Sodium is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov