产品名称

左乙拉西坦(Levetiracetam)

一般描述

Levetiracetam(左乙拉西坦) is a pyrrolidine with antiepileptic activity.

别 称

2(S)-(2-Oxopyrrolidin-1-yl)butyramide

纯 度

≥98%(HPLC)

CAS NO.

102767-28-2

分子式

C⁸H¹⁴N²O²

分子量

170.21

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥30mg/mL

乙醇

≥30mg/mL

水

≥30mg/mL

l  生物学信息

生物活性/药理作用

Levetiracetam is a pyrrolidine with antiepileptic activity. The exact mechanism through which levetiracetam exerts its effects is unknown but does not involve inhibitory and excitatory  neurotransmitter activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov