Pazopanib hydrochloride
商品编号：
TL0493
备注：
库存充足，如需更大包装，请联系销售人员，大包装有极大的折扣优惠！
详细介绍
l 基本信息 |
产品名称 | 盐酸帕唑帕尼(Pazopanib hydrochloride) |
一般描述 | Pazopanib hydrochloride(盐酸帕唑帕尼) is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. |
别 称 | 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride; GW 780604 |
纯 度 | ≥99.0%(HPLC) | CAS NO. | 635702-64-6 |
分子式 | C21H24ClN7O2S | 分子量 | 473.98 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色或类白色固体 |
溶解性(25℃) | DMSO | ≥15mg/mL |
乙醇 | Very
slightly soluble |
水 | Insoluble |
l 生物学信息 |
生物活性/药理作用 | Pazopanib Hydrochloride is the hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively
inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3,
c-kit and platelet derived growth factor receptor (PDGF-R), which may result
in inhibition of angiogenesis in tumors in which these receptors are upregulated. |
l 包装与存储 |
包 装 | 10mg; 25mg; 100mg; 500mg |
存储温度 | -20℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
