产品名称

Sulfacetamide sodium salt hydrate(磺胺乙酰钠盐水合物)

一般描述

Sulfacetamide sodium salt hydrate is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.

别 称

sodium;acetyl-(4-aminophenyl)sulfonylazanide; hydrate

纯 度

≥99.0%(HPLC)

CAS NO.

6209-17-2

分子式

C⁸H¹¹N²NaO⁴S

分子量

254.24

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

溶解性(25°C)

DMSO

≥35mg/ml

乙醇

Slightly soluble

水

≥35mg/ml

l  生物学信息

生物活性/药理作用

Sulfacetamide Sodium is the sodium salt form of sulfacetamide, a synthetic sulfanylacetamide derivative with bacteriostatic activity. Sulfacetamide inhibits bacterial folic acid synthesis by competing with para amino benzoic acid. With a broad spectrum of action, it is used as an anti-infective topical agent to treat skin infections and as an oral agent for urinary tract infections.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov