产品名称

Imiquimod(咪喹莫特)

一般描述

Imiquimod is a novel synthetic agent with immune response modifying activity.

别 称

R-837, S-26308; 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine

纯 度

≥98.0%(HPLC)

CAS NO.

99011-02-6

分子式

C¹⁴H¹⁶N⁴

分子量

240.31

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

Slightly soluble

乙醇

Insoluble

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Imiquimod is a synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 over in susceptible tumor cells.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov