产品名称

Terbinafine(特比萘芬)

一般描述

Terbinafine is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.

别 称

SF 86-327; (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine

纯 度

≥98.0%(HPLC)

CAS NO.

91161-71-6

分子式

C²¹H²⁵N

分子量

291.438

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥35mg/ml

乙醇

≥35mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Terbinafine is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov