Cortisone acetate
商品编号:
TS1062
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详细介绍
l 基本信息 |
产品名称 | Cortisone acetate(醋酸可的松) |
一般描述 | Cortisone acetate is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid. |
别 称 | Cortone; NSC 49420 |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 50-04-4 |
分子式 | C23H30O6 | 分子量 | 402.487 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 白色至类白色固体 |
溶解性(25°C) | DMSO | ~5mg/mL |
乙醇 | Insoluble |
水 | Insoluble |
l 生物学信息 |
生物活性/药理作用 | Cortisone Acetate is the acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA tranion. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |