产品名称

Harmine(哈尔碱)

一般描述

Harmine is an alkaloid of the β-carboline family that regulates PPARγ  through inhibition of the Wnt signaling pathway. It also selectively binds to MAO-A and reversibly inhibits monoamine oxidase A (MAO-A) but not the variant MAO-B.

别 称

telepathine; 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole

纯 度

≥98.0%(HPLC)

CAS NO.

442-51-3

分子式

C¹³H¹²N²O

分子量

212.252

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25°C)

DMSO

≥35mg/mL

l  生物学信息

生物活性/药理作用

Harmine is a harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7. It has a role as a metabolite, an anti-HIV agent and an EC 1.4.3.4 (monoamine oxidase) inhibitor. It derives from a hydride of a harman.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov