产品名称

Regadenoson(瑞加德松)

一般描述

Regadenoson is a selective A2A adenosine receptor agonist with coronary vasodilating activity.

别 称

CVT-3146, Lexiscan

纯 度

≥99.0%(HPLC)

CAS NO.

313348-27-5

分子式

C¹⁵H¹⁸N⁸O⁵

分子量

390.35402

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至米色固体

溶解性(25°C)

DMSO

≥50mg/ml

乙醇

Slightly soluble

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Regadenoson is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine receptor, which induces coronary vasodilation. This leads to an increase in coronary blood flow and enhances myocardial perfusion. Compared to adenosine, regadenoson has a longer half-life and shows higher selectivity towards the A2A adenosine receptor. This agent is a very weak agonist for the A1 adenosine receptor and has negligible affinity for the A2B and A3 adenosine receptors.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov