Tezacaftor(VX-661)
商品编号：
TS2892
备注：
如需更大包装，请联系销售人员，大包装有极大的折扣优惠！
详细介绍
l 基本信息 |
产品名称 | Tezacaftor |
一般描述 | Tezacaftor is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. |
别 称 | VX-661 |
纯 度 | ≥98.5%(HPLC) | CAS NO. | 1152311-62-0 |
分子式 | C26H27F3N2O6 | 分子量 | 520.5 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25°C) | DMSO | ≥50mg/ml |
乙醇 | Insoluble |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Tezacaftor is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function. It was developed by Vertex Pharmaceuticals and FDA approved in combination with ivacaftor; a CFTR potentiator that allows the proteins at the cell surface to open longer and improve nutrient transport. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
