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详细介绍
l 基本信息 |
产品名称 | E-64 |
一般描述 | E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. |
别 称 | Proteinase Inhibitor E 64; Thiol Protease Inhibitor |
纯 度 | ≥98.5%(HPLC) | CAS NO. | 66701-25-5 |
分子式 | C15H27N5O5 | 分子量 | 357.41 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25°C) | DMSO | ≥50mg/ml |
乙醇 | Insoluble |
水 | ≥5mg/ml |
l 生物学信息 |
生物活性/药理作用 | E64 is an epoxy monocarboxylic acid, a dicarboxylic acid monoamide, a member of guanidines and a L-leucine derivative. It has a role as a protease inhibitor, an antimalarial and an antiparasitic agent. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |