TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met.

Nilotinib hydrochloride(尼罗替尼盐酸盐) is the hydrochloride salt form of nilotinib, an orally bioavailable Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.

Y15(1,2,4,5-苯四胺四盐酸盐) is a small-molecule FAK scaffolding inhibitor that directly inhibits FAK autophosphorylation in a dose- and time-dependent manner.

BAY-61-3606 is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).

PP2, a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM in cell-free assays, ~100-fold less potent to EGFR, inactive for ZAP-70, JAK2 and PKA.

PP1 is a potent and selective Src inhibitor for Lck/Fyn with IC50 of 5 nM/ 6 nM.

RN486 is a potent and selective BTK inhibitor with IC50 of 4 nM.    

SSR128129E is an orally-active and allosteric FGFR1 inhibitor with IC50 of 1.9μM, while not affecting other related RTKs.