Proxyphylline(7-(2-羟丙基)茶碱) is a derivative of theophylline which is used as a bronchodilator and for its cardiovascular properties. It selectively antagonizes A1 adenosine receptors (Ki = 82 nM for bovine brain) versus A2 adenosine receptors (Ki = 850 nM for platelets).

Olivetol(3,5-二羟基戊苯) is a naturally occurring organic compound being a precursor in various syntheses of tetrahydrocannabinol. It acts as a competitive inhibitor of the cannabinoid receptors CB1 and CB2.

Regadenoson(瑞加德松) is a selective A2A adenosine receptor agonist with coronary vasodilating activity.

Ertugliflozin(埃格列净) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).

Dapagliflozin propanediol(达格列净丙二醇一水化物) belongs to the class of orally administered antidiabetic agents designated as sodiumglucose cotransporter 2 (SGLT2) inhibitors.

BMS-833923 is an orally bioavailable Smoothened antagonist.

Opaganib is an orally bioavailable and selective sphingosine kinase-2 (SphK2) inhibitor with IC50 of approximately 60 μM.

SKI II is a highly selective and non ATP-competitive sphingosine kinase (SphK) inhibitor with IC50 of 0.5 μM, while exhibiting no inhibitory action on other kinases including PI3K, PKCα and ERK2.