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  • DNA Ligase from T4-infected Escherichia coli
    TS2691

    Disopyramide(丙吡胺) is a class IA antiarrhythmic drug which acts via blockade of sodium channels depressing phase 0 of the action potential. Disopyramide possesses significant negative inotropic, anticholinergic effects and enhances AV nodal conduction.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2711

    Lanthanum(III) chloride(氯化镧七水合物) is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2750

    Sparteine Sulfate, a quinolizidine alkaloid, is the sulfate form of sparteini, which is a sodium channel blocker used as an oxytocic and an anti-arrhythmia agent.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2892

    Tezacaftor is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2916

    SC144 is the first-in-class orally active small-molecule gp130 inhibitor that induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the  of downstream target genes.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2973

    KPT-276 is an orally bioavailable selective CRM1 inhibitor.

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  • DNA Ligase from T4-infected Escherichia coli
    TS2981

    Golgicide A is a potent and rapidly reversible GBF1 inhibitor.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3008

    IOWH032 is a synthetic CFTR inhibitor with IC50 of 1.01 μM in CHO-CFTR cell based assays.

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